Interferon gamma Antikörper (AA 81-166)

Produktnummer ABIN669141

Dieser Anti-Interferon gamma Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von Interferon gamma in WB, ELISA, IHC (p), IHC (fro), IF (p) und IF (cc). Geeignet für Human. Dieses Primary Antibody wurde in 3+ Publikationen zitiert.

Kurzübersicht für Interferon gamma Antikörper (AA 81-166) (ABIN669141)

Target: Interferon gamma (IFNG)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Interferon gamma Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Produktdetails anti-Interferon gamma Antikörper

Bindungsspezifität: AA 81-166

Kreuzreaktivität: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IFN Gamma

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-Interferon gamma Antikörper (ABIN669141)

Wang, Wang, Song, Chu, Qu: "Deficiency of interferon-gamma or its receptor promotes colorectal cancer development." in: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, Vol. 35, Issue 4, pp. 273-80, (2015) (PubMed).

Nimmagadda, Bever, Vattikunta, Talat, Ahmad, Nagalla, Trisler, Judge, Royal, Chandrasekaran, Russell, Makar: "Overexpression of SIRT1 protein in neurons protects against experimental autoimmune encephalomyelitis through activation of multiple SIRT1 targets." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 190, Issue 9, pp. 4595-607, (2013) (PubMed).

Guo, Qian, Zhang: "Histopathology and immunohistochemical profile in idiopathic dacryoadenitis." in: Current eye research, Vol. 37, Issue 5, pp. 365-71, (2012) (PubMed).

Details zu Interferon gamma

Target: Interferon gamma (IFNG)

Andere Bezeichnung: IFN gamma

Hintergrund:

Synonyms: IFG, IFI, Interferon gamma, IFN-gamma, Immune interferon, IFNG

Background: Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.

Gen-ID: 3458

UniProt: P01579

Pathways: Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagie